Oral mucous squamous cell carcinoma—an anticipated consequence of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
BC Böckle, M Wilhelm, H Müller, C Götsch… - Journal of the American …, 2010 - Elsevier
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare
autosomal recessive disease caused by mutations in the AIRE gene. We report the case of a
female patient with a 967-979del13 mutation in the AIRE gene. Her medical history included
autoimmune hypoparathyroidism, Addison disease, and chronic mucocutaneous
candidiasis. At the age of 40, she developed multiple white verrucous plaques on the oral
mucosa. Histologically, the lesions appeared as moderately differentiated squamous cell …
autosomal recessive disease caused by mutations in the AIRE gene. We report the case of a
female patient with a 967-979del13 mutation in the AIRE gene. Her medical history included
autoimmune hypoparathyroidism, Addison disease, and chronic mucocutaneous
candidiasis. At the age of 40, she developed multiple white verrucous plaques on the oral
mucosa. Histologically, the lesions appeared as moderately differentiated squamous cell …