Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients
PO Gannon, AO Poisson, N Delvoye, R Lapointe… - Journal of …, 2009 - Elsevier
INTRODUCTION: Our goal was to study the hormonal regulation of immune cell infiltration in
prostate cancer patients treated by androgen deprivation therapy (ADT) using an optimized
computer-assistance quantification approach. METHODS: The relative density of immune
cell subtypes (CD3+, CD8+, CD20+, CD56+, CD68+ and Foxp3+) was analyzed by
immunohistochemistry in archived prostate specimens from control patients (radical
prostatectomy only, n= 40) and ADT-treated patients (ADT prior to radical prostatectomy, n …
prostate cancer patients treated by androgen deprivation therapy (ADT) using an optimized
computer-assistance quantification approach. METHODS: The relative density of immune
cell subtypes (CD3+, CD8+, CD20+, CD56+, CD68+ and Foxp3+) was analyzed by
immunohistochemistry in archived prostate specimens from control patients (radical
prostatectomy only, n= 40) and ADT-treated patients (ADT prior to radical prostatectomy, n …