Sex-based differences in skeletal muscle kinetics and fiber-type composition
KM Haizlip, BC Harrison, LA Leinwand - Physiology, 2015 - journals.physiology.org
KM Haizlip, BC Harrison, LA Leinwand
Physiology, 2015•journals.physiology.orgPrevious studies have identified over 3,000 genes that are differentially expressed in male
and female skeletal muscle. Here, we review the sex-based differences in skeletal muscle
fiber composition, myosin heavy chain expression, contractile function, and the regulation of
these physiological differences by thyroid hormone, estrogen, and testosterone. The findings
presented lay the basis for the continued work needed to fully understand the skeletal
muscle differences between males and females.
and female skeletal muscle. Here, we review the sex-based differences in skeletal muscle
fiber composition, myosin heavy chain expression, contractile function, and the regulation of
these physiological differences by thyroid hormone, estrogen, and testosterone. The findings
presented lay the basis for the continued work needed to fully understand the skeletal
muscle differences between males and females.
Previous studies have identified over 3,000 genes that are differentially expressed in male and female skeletal muscle. Here, we review the sex-based differences in skeletal muscle fiber composition, myosin heavy chain expression, contractile function, and the regulation of these physiological differences by thyroid hormone, estrogen, and testosterone. The findings presented lay the basis for the continued work needed to fully understand the skeletal muscle differences between males and females.
American Physiological Society