Antibodies to phospholipids represent a unique set of incompletely characterized antibodies
prevalent in patients with systemic lupus erythematosus and related autoimmune disorders.
Little is known concerning their induction and pathogenesis. Here we provide an overview of
what is currently known about these antibodies and explore the possibility that they interact
with and are perhaps specific for unusual lipid structures. Particular attention is given to the
physical chemical nature and phase behaviour of associated putative lipid antigens. This …