[HTML][HTML] Microbial minimalism: genome reduction in bacterial pathogens
NA Moran - Cell, 2002 - cell.com
Cell, 2002•cell.com
When bacterial lineages make the transition from free-living or facultatively parasitic life
cycles to permanent associations with hosts, they undergo a major loss of genes and DNA.
Complete genome sequences are providing an understanding of how extreme genome
reduction affects evolutionary directions and metabolic capabilities of obligate pathogens
and symbionts.
cycles to permanent associations with hosts, they undergo a major loss of genes and DNA.
Complete genome sequences are providing an understanding of how extreme genome
reduction affects evolutionary directions and metabolic capabilities of obligate pathogens
and symbionts.
Abstract
When bacterial lineages make the transition from free-living or facultatively parasitic life cycles to permanent associations with hosts, they undergo a major loss of genes and DNA. Complete genome sequences are providing an understanding of how extreme genome reduction affects evolutionary directions and metabolic capabilities of obligate pathogens and symbionts.
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