Anti-phospholipid antibody levels as biomarker for monitoring tuberculosis treatment response
A Goodridge, C Cueva, M Lahiff, G Muzanye… - Tuberculosis, 2012 - Elsevier
Standard methods to monitor tuberculosis (TB) treatment response rely on sputum
microscopy and culture conversion. Alternatives to these methods are needed for those
patients whose sputum tests are smear or culture negative. Here, we examine anti-
phospholipid IgM antibody level changes as a biomarker for treatment response in smear
positive TB patients. Serum samples were obtained from 40 pulmonary TB patients at the
start and end of the intensive phase treatment (IPT) from the CDC-TB Trials Consortium …
microscopy and culture conversion. Alternatives to these methods are needed for those
patients whose sputum tests are smear or culture negative. Here, we examine anti-
phospholipid IgM antibody level changes as a biomarker for treatment response in smear
positive TB patients. Serum samples were obtained from 40 pulmonary TB patients at the
start and end of the intensive phase treatment (IPT) from the CDC-TB Trials Consortium …