Predictors of endothelial function improvement in patients with mild hypertriglyceridemia without evidence of coronary artery disease treated with purified …

K Fukumoto, Y Takemoto, J Yoshikawa, N Norioka… - Atherosclerosis, 2020 - Elsevier
Background and aims Eicosapentaenoic acid (EPA) has been reported to reduce
cardiovascular risk in patients with hypertriglyceridemia. Although several mechanisms
underlying the effects of EPA have been demonstrated, those responsible for its beneficial
role in patients with hypertriglyceridemia without evidence of coronary artery disease (CAD)
have not been fully elucidated. We sought to clarify the main factors associated with EPA
administration that led to improved endothelial function. Methods Forty-seven consecutive …