Effects of lifetime noise exposure on the middle-age human auditory brainstem response, tinnitus and speech-in-noise intelligibility
JT Valderrama, EF Beach, I Yeend, M Sharma… - Hearing research, 2018 - Elsevier
Recent animal studies have shown that the synapses between inner hair cells and the
dendrites of the spiral ganglion cells they innervate are the elements in the cochlea most
vulnerable to excessive noise exposure. Particularly in rodents, several studies have
concluded that exposure to high level octave-band noise for 2 h leads to an irreversible loss
of around 50% of synaptic ribbons, leaving audiometric hearing thresholds unaltered.
Cochlear synaptopathy following noise exposure is hypothesized to degrade the neural …
dendrites of the spiral ganglion cells they innervate are the elements in the cochlea most
vulnerable to excessive noise exposure. Particularly in rodents, several studies have
concluded that exposure to high level octave-band noise for 2 h leads to an irreversible loss
of around 50% of synaptic ribbons, leaving audiometric hearing thresholds unaltered.
Cochlear synaptopathy following noise exposure is hypothesized to degrade the neural …