Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells
G Charkoftaki, DC Thompson, JP Golla… - Chemico-biological …, 2019 - Elsevier
Colorectal cancer (CRC) is the third most common cancer worldwide and one of the most
common diseases diagnosed in the USA among both men and women [1]. Interestingly, the
incidence and mortality rates have been declining in the United States over the past
decades for those aged over 50, with the pace accelerating to 3% annually from 2003 to
2012. However, there has been an alarming increase (51%) in colorectal cancer incidence
in those under 50 since 1994 [[2],[3],[4]]. The reasons for this increase are not fully …
common diseases diagnosed in the USA among both men and women [1]. Interestingly, the
incidence and mortality rates have been declining in the United States over the past
decades for those aged over 50, with the pace accelerating to 3% annually from 2003 to
2012. However, there has been an alarming increase (51%) in colorectal cancer incidence
in those under 50 since 1994 [[2],[3],[4]]. The reasons for this increase are not fully …