Background & Aims Our increasing understanding of hepatocellular carcinoma (HCC)
biology holds promise for personalized care, however its translation into clinical practice
requires a precise knowledge of its relationship to tumour phenotype. Methods We aimed at
investigating molecular-phenotypic correlations in a large series of HCC. To this purpose,
343 surgically resected HCC samples were investigated by pathological review,
immunohistochemistry, gene expression profiling and sequencing. Results CTNNB1 (40%) …