[HTML][HTML] Intragastric infusion of denatonium benzoate attenuates interdigestive gastric motility and hunger scores in healthy female volunteers
E Deloose, P Janssen, M Corsetti… - The American Journal of …, 2017 - Elsevier
Background: Denatonium benzoate (DB) has been shown to influence ongoing ingestive
behavior and gut peptide secretion. Objective: We studied how the intragastric
administration of DB affects interdigestive motility, motilin and ghrelin plasma
concentrations, hunger and satiety ratings, and food intake in healthy volunteers. Design:
Lingual bitter taste sensitivity was tested with the use of 6 concentrations of DB in 65
subjects. A placebo or 1 μmol DB/kg was given intragastrically to assess its effect on fasting …
behavior and gut peptide secretion. Objective: We studied how the intragastric
administration of DB affects interdigestive motility, motilin and ghrelin plasma
concentrations, hunger and satiety ratings, and food intake in healthy volunteers. Design:
Lingual bitter taste sensitivity was tested with the use of 6 concentrations of DB in 65
subjects. A placebo or 1 μmol DB/kg was given intragastrically to assess its effect on fasting …