[HTML][HTML] Comprehensive analysis of mouse bitter taste receptors reveals different molecular receptive ranges for orthologous receptors in mice and humans
K Lossow, S Hübner, N Roudnitzky, JP Slack… - Journal of Biological …, 2016 - ASBMB
One key to animal survival is the detection and avoidance of potentially harmful compounds
by their bitter taste. Variable numbers of taste 2 receptor genes expressed in the gustatory
end organs enable bony vertebrates (Euteleostomi) to recognize numerous bitter chemicals.
It is believed that the receptive ranges of bitter taste receptor repertoires match the profiles of
bitter chemicals that the species encounter in their diets. Human and mouse genomes
contain pairs of orthologous bitter receptor genes that have been conserved throughout …
by their bitter taste. Variable numbers of taste 2 receptor genes expressed in the gustatory
end organs enable bony vertebrates (Euteleostomi) to recognize numerous bitter chemicals.
It is believed that the receptive ranges of bitter taste receptor repertoires match the profiles of
bitter chemicals that the species encounter in their diets. Human and mouse genomes
contain pairs of orthologous bitter receptor genes that have been conserved throughout …