[HTML][HTML] Imbalance in T-helper 17 cells and targeted therapy in an infant with SAM-like syndrome

A Hernández-Martín, R Kennedy-Batalla… - … England Journal of …, 2019 - Mass Medical Soc
A Hernández-Martín, R Kennedy-Batalla, E Cañedo, E Bernaldo-de-Quirós
New England Journal of Medicine, 2019Mass Medical Soc
T-Helper 17 Cells in Genetic Dermatitis An infant with SAM-like syndrome (severe dermatitis,
allergies, and metabolic wasting) was found to have a substantial increase in the number of
T-helper 17 cells. Administration of the monoclonal antibody secukinumab produced
remarkable improvement, with symptom relief and restoration of normal growth.
T-Helper 17 Cells in Genetic Dermatitis
An infant with SAM-like syndrome (severe dermatitis, allergies, and metabolic wasting) was found to have a substantial increase in the number of T-helper 17 cells. Administration of the monoclonal antibody secukinumab produced remarkable improvement, with symptom relief and restoration of normal growth.
The New England Journal Of Medicine