[CITATION][C] Studies on succinate dehydrogenase: I. Spectral properties of the purified enzyme and formation of enzyme-competitive inhibitor complexes
DV Dervartanian, C Veeger - … et Biophysica Acta (BBA)-Specialized Section …, 1964 - Elsevier
1. Succinate dehydrogenase (succinate:(acceptor) oxidoreductase, EC 1.3. 99.1) reacts
immediately with competitive inhibitors to form spectrally detectable enzyme-inhibitor
complexes, which are converted to succinate-reduced enzyme on the subsequent addition
of succinate. 2. 2. The enzyme-inhibitor complexes formed with malonate, fumarate, maleate
and methylene succinate differ from that with oxaloacetate in spectral characteristics, the
latter showing a wide, diffuse band from 500 to 750 mμ. 3. 3. Pyrophosphate, a strong …
immediately with competitive inhibitors to form spectrally detectable enzyme-inhibitor
complexes, which are converted to succinate-reduced enzyme on the subsequent addition
of succinate. 2. 2. The enzyme-inhibitor complexes formed with malonate, fumarate, maleate
and methylene succinate differ from that with oxaloacetate in spectral characteristics, the
latter showing a wide, diffuse band from 500 to 750 mμ. 3. 3. Pyrophosphate, a strong …