[PDF][PDF] B cell memory: understanding COVID-19

I Quast, D Tarlinton - Immunity, 2021 - cell.com
Immunity, 2021cell.com
Immunological memory is a mechanism to protect us against reinfection. Antibodies
produced by B cells are integral to this defense strategy and underlie virtually all vaccine
success. Here, we explain how B cell memory is generated by infection and vaccination,
what influences its efficacy and its persistence, and how characterizing these parameters in
the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
will help achieve protective immunity through vaccination.
Immunological memory is a mechanism to protect us against reinfection. Antibodies produced by B cells are integral to this defense strategy and underlie virtually all vaccine success. Here, we explain how B cell memory is generated by infection and vaccination, what influences its efficacy and its persistence, and how characterizing these parameters in the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will help achieve protective immunity through vaccination.
cell.com