The effects of hydroxychloroquine on endothelial dysfunction

R Rahman, P Murthi, H Singh, S Gurusinghe… - … An International Journal …, 2016 - Elsevier
Hydroxychloroquine is an anti-malarial drug which, due to its anti-inflammatory and
immunomodulatory effects, is widely used for the treatment of autoimmune diseases. In a
model of systemic lupus erythematosus hydroxychloroquine has been shown to exert
protective endothelial effects. In this study, we aimed to investigate whether
hydroxychloroquine was endothelial protective in an in vitro model of TNF-α and
preeclamptic serum induced dysfunction. We showed that hydroxychloroquine significantly …