Statin reduces mortality and morbidity in systemic lupus erythematosus patients with hyperlipidemia: a nationwide population-based cohort study

HH Yu, PC Chen, YH Yang, LC Wang, JH Lee, YT Lin… - Atherosclerosis, 2015 - Elsevier
Objective The anti-inflammatory and cardiovascular protective effects of statin for patients
with systemic lupus erythematosus (SLE) are not clear. We tested the hypothesis that statin
use is associated with reduced mortality and morbidity in SLE patients with hyperlipidemia.
Methods We included 4095 patients with SLE and hyperlipidemia from the entire population
using the Taiwan National Health Insurance Research Database between 1997 and 2008. A
total of 935 matching sets (1: 2) of patients who had never used lipid-lowering medications …