Uremia

TW Meyer, TH Hostetter - New England Journal of Medicine, 2007 - Mass Medical Soc
TW Meyer, TH Hostetter
New England Journal of Medicine, 2007Mass Medical Soc
The meaning of uremia, which refers to the illness accompanying kidney failure that is
unexplained by derangements in extracellular volume, inorganic ion concentrations, or lack
of known renal synthetic products, has changed. We now assume that uremic illness is due
largely to the accumulation of organic waste products, not all identified, that are normally
cleared by the kidneys. This review considers the pathogenesis and course of uremia.
The meaning of uremia, which refers to the illness accompanying kidney failure that is unexplained by derangements in extracellular volume, inorganic ion concentrations, or lack of known renal synthetic products, has changed. We now assume that uremic illness is due largely to the accumulation of organic waste products, not all identified, that are normally cleared by the kidneys. This review considers the pathogenesis and course of uremia.
The New England Journal Of Medicine