ALCAM a novel biomarker in patients with type 2 diabetes mellitus complicated with diabetic nephropathy
A Sulaj, S Kopf, E Gröne, HJ Gröne, S Hoffmann… - Journal of Diabetes and …, 2017 - Elsevier
Abstract Background & Aim Activated leukocyte cell adhesion molecule (ALCAM/CD166)
functions analogue to the receptor of advanced glycation end products, which has been
implicated in the development of diabetic nephropathy (DN). We investigated the expression
of ALCAM and its ligand S100B in patients with DN. Methods A total of 34 non-diabetic
patients, 29 patients with type 2 diabetes and normal albuminuria and 107 patients with type
2 diabetes complicated with DN were assessed for serum concentration of soluble ALCAM …
functions analogue to the receptor of advanced glycation end products, which has been
implicated in the development of diabetic nephropathy (DN). We investigated the expression
of ALCAM and its ligand S100B in patients with DN. Methods A total of 34 non-diabetic
patients, 29 patients with type 2 diabetes and normal albuminuria and 107 patients with type
2 diabetes complicated with DN were assessed for serum concentration of soluble ALCAM …