Expression and regulation of activated leukocyte cell adhesion molecule in human retinal vascular endothelial cells
JR Smith, TJ Chipps, H Ilias, Y Pan… - Experimental eye …, 2012 - Elsevier
Activated leukocyte cell adhesion molecule (ALCAM; CD166) is an immunoglobulin
superfamily member that has been described in several non-ocular endothelial populations,
but not in relation to endothelium within the eye. Studies in extraocular systems have
implicated ALCAM in angiogenesis and leukocyte transendothelial migration, which are key
processes in retinal vascular diseases. We investigated the expression of ALCAM in human
retinal endothelium, and studied the regulation of expression by established angiogenic and …
superfamily member that has been described in several non-ocular endothelial populations,
but not in relation to endothelium within the eye. Studies in extraocular systems have
implicated ALCAM in angiogenesis and leukocyte transendothelial migration, which are key
processes in retinal vascular diseases. We investigated the expression of ALCAM in human
retinal endothelium, and studied the regulation of expression by established angiogenic and …