ELISA for human serum leucine-rich alpha-2-glycoprotein-1 employing cytochrome c as the capturing ligand
S Weivoda, JD Andersen, A Skogen… - Journal of …, 2008 - Elsevier
Leucine-rich alpha-2-glycoprotein-1 (LRG) is a serum glycoprotein of unknown function that
has shown promise based on qualitative assessments as a biomarker for certain diseases
including microbial infections and cancer. However, the lack of a quantitative assay for LRG
has limited its application. Here an indirect enzyme-linked immunosorbent assay (ELISA) for
quantifying LRG in human serum is described in which cytochrome c is employed as the
capturing ligand and a monoclonal antibody specific for LRG is used to detect the captured …
has shown promise based on qualitative assessments as a biomarker for certain diseases
including microbial infections and cancer. However, the lack of a quantitative assay for LRG
has limited its application. Here an indirect enzyme-linked immunosorbent assay (ELISA) for
quantifying LRG in human serum is described in which cytochrome c is employed as the
capturing ligand and a monoclonal antibody specific for LRG is used to detect the captured …