Phagocytosis can be induced via the engagement of Fcγ receptors by antibody-opsonized
material. Furthermore, the efficiency of antibody-induced effector functions has been shown
to be dramatically modulated by changes in antibody glycosylation. Because infection can
modulate antibody glycans, which in turn modulate antibody functions, assays capable of
determining the induction of effector functions rather than neutralization or titer provide a
valuable opportunity to more fully characterize the quality of the adaptive immune response …