Investigation of the bone and the bone marrow is critical in many research fields including
basic bone biology, immunology, hematology, cancer metastasis, biomechanics, and stem
cell biology. Despite the importance of the bone in healthy and pathologic states, however, it
is a largely under-researched organ due to lack of specialized knowledge of bone dissection
and bone marrow isolation. Mice are a common model organism to study effects on bone
and bone marrow, necessitating a standardized and efficient method for long bone …