Presence of genetic variants among young men with severe COVID-19
CI Van Der Made, A Simons, J Schuurs-Hoeijmakers… - Jama, 2020 - jamanetwork.com
Importance Severe coronavirus disease 2019 (COVID-19) can occur in younger,
predominantly male, patients without preexisting medical conditions. Some individuals may
have primary immunodeficiencies that predispose to severe infections caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Objective To explore the presence
of genetic variants associated with primary immunodeficiencies among young patients with
COVID-19. Design, Setting, and Participants Case series of pairs of brothers without medical …
predominantly male, patients without preexisting medical conditions. Some individuals may
have primary immunodeficiencies that predispose to severe infections caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Objective To explore the presence
of genetic variants associated with primary immunodeficiencies among young patients with
COVID-19. Design, Setting, and Participants Case series of pairs of brothers without medical …