Fluoxetine decreases fat and protein intakes but not carbohydrate intake in male rats

LK Heisler, RB Kanarek, A Gerstein - Pharmacology Biochemistry and …, 1997 - Elsevier
Administration of fluoxetine, a selective serotonin reuptake inhibitor, results in decreases in
food intake and body weight. The present study investigated whether the anorectic actions of
fluoxetine were due to a general decrease in caloric intake or macronutrient specific. Male
Long–Evans rats were maintained on a dietary self-selection regime with separate sources
of protein, fat, and carbohydrate. During the acute phase of the experiment, nutrient intakes
were measured 2, 4, 6, and 24 h after injections of 0, 5.0, and 10.0 mg/kg fluoxetine …