Apolipoprotein L1 risk variants associate with systemic lupus erythematosus-associated collapsing glomerulopathy
CP Larsen, ML Beggs, M Saeed… - Journal of the American …, 2013 - journals.lww.com
Collapsing glomerulopathy is a devastating renal disease that primarily affects African
Americans and associates with numerous etiologies, such as HIV and autoimmune disease.
The presence of APOL1 risk alleles associates with HIV-associated collapsing
glomerulopathy, but it is unknown whether these risk alleles also associate with systemic
lupus erythematosus (SLE)-associated collapsing glomerulopathy. Here, re-examination of
546 renal biopsies from African-American patients with SLE identified 26 cases of collapsing …
Americans and associates with numerous etiologies, such as HIV and autoimmune disease.
The presence of APOL1 risk alleles associates with HIV-associated collapsing
glomerulopathy, but it is unknown whether these risk alleles also associate with systemic
lupus erythematosus (SLE)-associated collapsing glomerulopathy. Here, re-examination of
546 renal biopsies from African-American patients with SLE identified 26 cases of collapsing …