Effects of biosolubility on pulmonary uptake and disposition of gases and vapors of lipophilic chemicals
V Fiserova-bergerova, M Tichy… - Drug Metabolism …, 1984 - Taylor & Francis
V Fiserova-bergerova, M Tichy, FJ di Carlo
Drug Metabolism Reviews, 1984•Taylor & FrancisI1. EXPERIMENTAL...................................... A. Simulation Model................................. R.
Determination of Tissue-Gas Partition Coefficients..................................... C. Intercorrelation of
Tissue-Gas Partition Coefficients of Selected Lipophilic Chemicals.......................................
Correlation of Tissue-Gas Partition Coefficients with Oil-Gas Partition Coefficients and
Octanol-Water Distribution Coefficients................... Estimation of Oil-Gas Partition Coefficients
from Molecular Connectivity.......................
Determination of Tissue-Gas Partition Coefficients..................................... C. Intercorrelation of
Tissue-Gas Partition Coefficients of Selected Lipophilic Chemicals.......................................
Correlation of Tissue-Gas Partition Coefficients with Oil-Gas Partition Coefficients and
Octanol-Water Distribution Coefficients................... Estimation of Oil-Gas Partition Coefficients
from Molecular Connectivity.......................
I1. EXPERIMENTAL...................................... A. Simulation Model................................. R. Determination of Tissue-Gas Partition Coefficients..................................... C. Intercorrelation of Tissue-Gas Partition Coefficients of Selected Lipophilic Chemicals....................................... Correlation of Tissue-Gas Partition Coefficients with Oil-Gas Partition Coefficients and Octanol-Water Distribution Coefficients................... Estimation of Oil-Gas Partition Coefficients from Molecular Connectivity.......................
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