Background Apolipoprotein C3 (APOC3) is a risk factor for incident coronary artery disease
in people with type 1 diabetes (T1D). The pathways that link elevated APOC3 levels to an
increased risk of incident cardiovascular disease in people with T1D are not understood.
Objective To explore potential mechanisms, we investigated the association of APOC3 with
insulin resistance and coronary artery calcium (CAC). Methods In a random subcohort of
participants with T1D from Coronary Artery Calcification in Type 1 Diabetes (n= 134), serum …