[HTML][HTML] Duration of infectiousness and correlation with RT-PCR cycle threshold values in cases of COVID-19, England, January to May 2020
A Singanayagam, M Patel, A Charlett… - …, 2020 - eurosurveillance.org
Eurosurveillance, 2020•eurosurveillance.org
Severe acute respiratory syndrome coronavirus 2 viral load in the upper respiratory tract
peaks around symptom onset and infectious virus persists for 10 days in mild-to-moderate
coronavirus disease (n= 324 samples analysed). RT-PCR cycle threshold (Ct) values
correlate strongly with cultivable virus. Probability of culturing virus declines to 8% in
samples with Ct> 35 and to 6% 10 days after onset; it is similar in asymptomatic and
symptomatic persons. Asymptomatic persons represent a source of transmissible virus.
peaks around symptom onset and infectious virus persists for 10 days in mild-to-moderate
coronavirus disease (n= 324 samples analysed). RT-PCR cycle threshold (Ct) values
correlate strongly with cultivable virus. Probability of culturing virus declines to 8% in
samples with Ct> 35 and to 6% 10 days after onset; it is similar in asymptomatic and
symptomatic persons. Asymptomatic persons represent a source of transmissible virus.
Severe acute respiratory syndrome coronavirus 2 viral load in the upper respiratory tract peaks around symptom onset and infectious virus persists for 10 days in mild-to-moderate coronavirus disease (n = 324 samples analysed). RT-PCR cycle threshold (Ct) values correlate strongly with cultivable virus. Probability of culturing virus declines to 8% in samples with Ct > 35 and to 6% 10 days after onset; it is similar in asymptomatic and symptomatic persons. Asymptomatic persons represent a source of transmissible virus.
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