Panel of reactive T cells as a measurement of primed cellular alloimmunity in kidney transplant candidates
ED Poggio, M Clemente, DE Hricik… - Journal of the American …, 2006 - journals.lww.com
Pretransplantation panel reactive antibody (PRA) testing assesses posttransplantation risk
for antibody-mediated graft injury. It was postulated analogously that screening for
effector/memory alloreactive T cells by “panel of reactive T cells”(PRT) using IFN-γ enzyme-
linked immunosorbent spot assays would evaluate independently cellular alloimmunity in
transplant candidates. Peripheral blood lymphocytes from 41 hemodialysis patients who
were awaiting first renal transplants were tested against a panel of allogeneic stimulator …
for antibody-mediated graft injury. It was postulated analogously that screening for
effector/memory alloreactive T cells by “panel of reactive T cells”(PRT) using IFN-γ enzyme-
linked immunosorbent spot assays would evaluate independently cellular alloimmunity in
transplant candidates. Peripheral blood lymphocytes from 41 hemodialysis patients who
were awaiting first renal transplants were tested against a panel of allogeneic stimulator …