The cortisol and glucocorticoid receptor response to low dose dexamethasone administration in aging combat veterans and holocaust survivors with and without …

R Yehuda, SL Halligan, R Grossman, JA Golier… - Biological …, 2002 - Elsevier
Background: Because alterations in cortisol negative feedback inhibition associated with
aging are generally opposite of those observed in posttraumatic stress disorder (PTSD), we
examined the cortisol and glucocorticoid receptor (GR) response to dexamethasone (DEX)
in older trauma survivors. Methods: Twenty-three Holocaust survivors (9 men, 14 women),
27 combat veterans (all male), and 10 comparison subjects (7 men, 3 women) provided
samples for plasma or salivary cortisol and glucocorticoid receptor determination in …