Convalescent plasma for infectious diseases: historical framework and use in COVID-19

JG Ripoll, N van Helmond, JW Senefeld… - Clinical Microbiology …, 2021 - Elsevier
Convalescent plasma has emerged as a promising therapeutic agent for patients with
coronavirus disease 2019 (COVID-19), has received emergency use authorization, and is
being widely used during the COVID-19 pandemic. Passive antibody therapy via plasma or
serum has been successfully used to treat infectious diseases for more than a century.
Passive antibody administration is based on the presumption that convalescent plasma or
serum contains therapeutic antibodies that can be passively transferred to the plasma …