Does the cell number 109 still really fit one gram of tumor tissue?
U Del Monte - Cell cycle, 2009 - Taylor & Francis
U Del Monte
Cell cycle, 2009•Taylor & FrancisA tumor reaching the size of 1 cm3 (approximately 1 g wet weight) is commonly assumed to
contain 1 x 109 cells. This paper comments on the probable origin of this “magic” number
and on some possible reasons why it has remained in use until now. However, mostly in
epithelial tumors (85% of all human tumors) a cell number one order of magnitude smaller
would be more realistic.
contain 1 x 109 cells. This paper comments on the probable origin of this “magic” number
and on some possible reasons why it has remained in use until now. However, mostly in
epithelial tumors (85% of all human tumors) a cell number one order of magnitude smaller
would be more realistic.
A tumor reaching the size of 1 cm3 (approximately 1 g wet weight) is commonly assumed to contain 1 x 109 cells. This paper comments on the probable origin of this “magic” number and on some possible reasons why it has remained in use until now. However, mostly in epithelial tumors (85% of all human tumors) a cell number one order of magnitude smaller would be more realistic.
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