Myocardial infarction in the C57BL/6J mouse: a quantifiable and highly reproducible experimental model
M Salto-Tellez, SY Lim, RM El Oakley, TPL Tang… - Cardiovascular …, 2004 - Elsevier
INTRODUCTION: The laboratory mouse is a powerful tool in cardiovascular research. In this
report, we describe a method for a reproducible mouse myocardial infarction model that
would allow subsequent comparative and quantitative studies on molecular and
pathophysiological variables. METHODS:(A) The distribution of the major coronary arteries
including the septal artery in the left ventricle of the C57BL/6J mice (n= 20) was mapped by
perfusion of latex dye or fluorescent beads through the aorta.(B) The territory of myocardial …
report, we describe a method for a reproducible mouse myocardial infarction model that
would allow subsequent comparative and quantitative studies on molecular and
pathophysiological variables. METHODS:(A) The distribution of the major coronary arteries
including the septal artery in the left ventricle of the C57BL/6J mice (n= 20) was mapped by
perfusion of latex dye or fluorescent beads through the aorta.(B) The territory of myocardial …
