[HTML][HTML] Improved metagenomic analysis with Kraken 2
Genome biology, 2019•Springer
Although Kraken'sk-mer-based approach provides a fast taxonomic classification of
metagenomic sequence data, its large memory requirements can be limiting for some
applications. Kraken 2 improves upon Kraken 1 by reducing memory usage by 85%,
allowing greater amounts of reference genomic data to be used, while maintaining high
accuracy and increasing speed fivefold. Kraken 2 also introduces a translated search mode,
providing increased sensitivity in viral metagenomics analysis.
metagenomic sequence data, its large memory requirements can be limiting for some
applications. Kraken 2 improves upon Kraken 1 by reducing memory usage by 85%,
allowing greater amounts of reference genomic data to be used, while maintaining high
accuracy and increasing speed fivefold. Kraken 2 also introduces a translated search mode,
providing increased sensitivity in viral metagenomics analysis.
Abstract
Although Kraken’s k-mer-based approach provides a fast taxonomic classification of metagenomic sequence data, its large memory requirements can be limiting for some applications. Kraken 2 improves upon Kraken 1 by reducing memory usage by 85%, allowing greater amounts of reference genomic data to be used, while maintaining high accuracy and increasing speed fivefold. Kraken 2 also introduces a translated search mode, providing increased sensitivity in viral metagenomics analysis.
Springer