Localisation and neural control of the release of calcitonin gene-related peptide (CGRP) from the isolated perfused porcine ileum
TN Rasmussen, P Schmidt, SS Poulsen, JJ Holst - Regulatory peptides, 2001 - Elsevier
By immunohistochemistry, CGRP-like immunoreactive (CGRP-LI) nerve fibres were found in
the lamina propria along small vessels and in the lamina muscularis mucosae in the porcine
ileum. Immunoreactive nerve cell bodies were found in the submucous and myenteric
plexus. Upon HPLC-analysis of ileal extracts, CGRP-LI corresponded entirely to porcine
CGRP plus smaller amounts of oxidised CGRP. Using isolated vascularly perfused
segments of the ileum, we studied the release of CGRP-LI in response to electrical …
the lamina propria along small vessels and in the lamina muscularis mucosae in the porcine
ileum. Immunoreactive nerve cell bodies were found in the submucous and myenteric
plexus. Upon HPLC-analysis of ileal extracts, CGRP-LI corresponded entirely to porcine
CGRP plus smaller amounts of oxidised CGRP. Using isolated vascularly perfused
segments of the ileum, we studied the release of CGRP-LI in response to electrical …
