[HTML][HTML] Phospholipid subcellular localization and dynamics

Y Yang, M Lee, GD Fairn - Journal of Biological Chemistry, 2018 - ASBMB
Membrane biology seeks to understand how lipids and proteins within bilayers assemble
into large structures such as organelles and the plasma membranes. Historically, lipids were
thought to merely provide structural support for bilayer formation and membrane protein
function. Research has now revealed that phospholipid metabolism regulates nearly all
cellular processes. Sophisticated techniques helped identify> 10,000 lipid species
suggesting that lipids support many biological processes. Here, we highlight the synthesis of …