Molecular genetics of thyroid cancer in children and adolescents

AJ Bauer - Endocrinology and Metabolism Clinics, 2017 - endo.theclinics.com
In the simplest approach, thyroid cancer is divided into 2 major categories: follicularderived
tumors, including follicular thyroid carcinoma (FTC) and papillary thyroid carcinoma (PTC),
and the parafollicular-derived tumor, medullary thyroid carcinoma (MTC). FTC and PTC are
often classified as forms of differentiated thyroid cancer (DTC) because they typically
maintain nonmalignant cellular physiology, including the ability to respond to thyroid
stimulatory hormone (TSH), transport iodine via the sodium-iodine symporter, and produce …