[HTML][HTML] The low density lipoprotein receptor-related protein complexes with cell surface heparan sulfate proteoglycans to regulate proteoglycan-mediated lipoprotein …
LC Wilsie, RA Orlando - Journal of Biological Chemistry, 2003 - ASBMB
It has been proposed that clearance of cholesterol-enriched very low density lipoprotein
(VLDL) particles occurs through a multistep process beginning with their initial binding to
cell-surface heparan sulfate proteoglycans (HSPG), followed by their uptake into cells by a
receptor-mediated process that utilizes members of the low density lipoprotein receptor
(LDLR) family, including the low density lipoprotein receptor-related protein (LRP). We have
further explored the relationship between HSPG binding of VLDL and its subsequent …
(VLDL) particles occurs through a multistep process beginning with their initial binding to
cell-surface heparan sulfate proteoglycans (HSPG), followed by their uptake into cells by a
receptor-mediated process that utilizes members of the low density lipoprotein receptor
(LDLR) family, including the low density lipoprotein receptor-related protein (LRP). We have
further explored the relationship between HSPG binding of VLDL and its subsequent …