Characterization of immunoglobulins and cytokines in human cervical mucus: influence of exogenous and endogenous hormones

RD Franklin, WH Kutteh - Journal of reproductive immunology, 1999 - Elsevier
Mucosal immunity in the female reproductive tract is influenced by immunoglobulins (Igs),
cytokines, and reproductive hormones. Previous studies of reproductive-aged women
demonstrated that IgA and IgG increases in cervical mucus corresponded to elevated levels
of IL-1β which occurred 1 day before the peak of endogenous estradiol production prior to
ovulation. We sought to determine the effect of exogenous hormones on reproductive tract
immunity in women on oral contraceptive pills (OCPs) and to compare the results with …