[HTML][HTML] Identification of novel HIV-1-derived HLA-E-binding peptides
Z Hannoun, Z Lin, S Brackenridge, N Kuse… - Immunology …, 2018 - Elsevier
Non-classical class Ib MHC-E molecule is becoming an increasingly interesting component
of the immune response. It is involved in both the adaptive and innate immune responses to
several chronic infections including HIV-1 and, under very specific circumstances, likely
mediated a unique vaccine protection of rhesus macaques against pathogenic SIV
challenge. Despite being recently in the spotlight for HIV-1 vaccine development, to date
there is only one reported human leukocyte antigen (HLA)-E-binding peptide derived from …
of the immune response. It is involved in both the adaptive and innate immune responses to
several chronic infections including HIV-1 and, under very specific circumstances, likely
mediated a unique vaccine protection of rhesus macaques against pathogenic SIV
challenge. Despite being recently in the spotlight for HIV-1 vaccine development, to date
there is only one reported human leukocyte antigen (HLA)-E-binding peptide derived from …