[PDF][PDF] miRNAs in development and pathogenesis of the nervous system.
JS Nowak, G Michlewski - Biochemical Society transactions, 2013 - academia.edu
JS Nowak, G Michlewski
Biochemical Society transactions, 2013•academia.eduThe human nervous system expresses approximately 70% of all miRNAs (microRNAs).
Changing levels of certain ubiquitous and brain-specific miRNAs shape the development
and function of the nervous system. It is becoming clear that misexpression of some miRNAs
can contribute towards neurodevelopmental disorders. In the present article, we review the
current knowledge of the role of miRNAs in development and pathogenesis of the nervous
system.
Changing levels of certain ubiquitous and brain-specific miRNAs shape the development
and function of the nervous system. It is becoming clear that misexpression of some miRNAs
can contribute towards neurodevelopmental disorders. In the present article, we review the
current knowledge of the role of miRNAs in development and pathogenesis of the nervous
system.
Abstract
The human nervous system expresses approximately 70% of all miRNAs (microRNAs). Changing levels of certain ubiquitous and brain-specific miRNAs shape the development and function of the nervous system. It is becoming clear that misexpression of some miRNAs can contribute towards neurodevelopmental disorders. In the present article, we review the current knowledge of the role of miRNAs in development and pathogenesis of the nervous system.
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