The severity of Streptococcus pyogenes infections in children is significantly associated with plasma levels of inflammatory cytokines
SM Wang, IH Lu, YL Lin, YS Lin, JJ Wu… - … and infectious disease, 2008 - Elsevier
Cytokines are intimately involved with the innate and adaptive immune response to bacterial
infections. This study was designed to determine the expression of inflammatory cytokines in
children by the severity of Streptococcus pyogenes (group A Streptococcus [GAS])
infections. The study population consisted of 16 invasive, 20 noninvasive, and 24
pharyngeal colonization, and 21 healthy controls. All children underwent the laboratory tests
and cytokine measurement. GAS isolates were analyzed for emm gene typing. Patients with …
infections. This study was designed to determine the expression of inflammatory cytokines in
children by the severity of Streptococcus pyogenes (group A Streptococcus [GAS])
infections. The study population consisted of 16 invasive, 20 noninvasive, and 24
pharyngeal colonization, and 21 healthy controls. All children underwent the laboratory tests
and cytokine measurement. GAS isolates were analyzed for emm gene typing. Patients with …