Immunotherapy for lethal prostate cancer

P Rescigno, JS de Bono - Nature Reviews Urology, 2019 - nature.com
Nature Reviews Urology, 2019nature.com
Immunotherapy and tumour microenvironment modulation are potential new treatment
approaches for metastatic prostate cancer, but patient selection might be key to delivering
therapeutic benefit. In the past year, four studies have suggested that DNA mismatch repair
alterations and CDK12 aberrations are biomarkers of response to immune checkpoint
inhibitors.
Immunotherapy and tumour microenvironment modulation are potential new treatment approaches for metastatic prostate cancer, but patient selection might be key to delivering therapeutic benefit. In the past year, four studies have suggested that DNA mismatch repair alterations and CDK12 aberrations are biomarkers of response to immune checkpoint inhibitors.
nature.com