Effect of dexamethasone on days alive and ventilator-free in patients with moderate or severe acute respiratory distress syndrome and COVID-19: the CoDEX …
Importance Acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019
(COVID-19) is associated with substantial mortality and use of health care resources.
Dexamethasone use might attenuate lung injury in these patients. Objective To determine
whether intravenous dexamethasone increases the number of ventilator-free days among
patients with COVID-19–associated ARDS. Design, Setting, and Participants Multicenter,
randomized, open-label, clinical trial conducted in 41 intensive care units (ICUs) in Brazil …
(COVID-19) is associated with substantial mortality and use of health care resources.
Dexamethasone use might attenuate lung injury in these patients. Objective To determine
whether intravenous dexamethasone increases the number of ventilator-free days among
patients with COVID-19–associated ARDS. Design, Setting, and Participants Multicenter,
randomized, open-label, clinical trial conducted in 41 intensive care units (ICUs) in Brazil …