COVID-19 does not lead to a “typical” acute respiratory distress syndrome
L Gattinoni, S Coppola, M Cressoni… - American journal of …, 2020 - atsjournals.org
American journal of respiratory and critical care medicine, 2020•atsjournals.org
In summary, we found that hypercapnia was common in patients with COVID-19–associated
ARDS while using low VT ventilation. VR was increased in these patients, which reflected
increased pulmonary dead space and inadequacy of ventilation. An intermediate VT was
used to correct hypercapnia efficiently, while not excessively increasing driving pressure.
Clinicians must have a high index of suspicion for increased pulmonary dead space when
patients with COVID-19–related ARDS present with hypercapnia.■
ARDS while using low VT ventilation. VR was increased in these patients, which reflected
increased pulmonary dead space and inadequacy of ventilation. An intermediate VT was
used to correct hypercapnia efficiently, while not excessively increasing driving pressure.
Clinicians must have a high index of suspicion for increased pulmonary dead space when
patients with COVID-19–related ARDS present with hypercapnia.■
In summary, we found that hypercapnia was common in patients with COVID-19–associated ARDS while using low VT ventilation. VR was increased in these patients, which reflected increased pulmonary dead space and inadequacy of ventilation. An intermediate VT was used to correct hypercapnia efficiently, while not excessively increasing driving pressure. Clinicians must have a high index of suspicion for increased pulmonary dead space when patients with COVID-19–related ARDS present with hypercapnia.■
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