It has been known that the gut microbiota plays a central role in shaping normal mucosal
immunity, however, little information is available whether the variability of mucosal
lymphocytes impacts the commensal flora. Here, we applied a cynomolgus monkey model to
characterize the structure and composition of the gut microbiota in response to lymphocyte
depletion and to determine their potential association. Molecular profiling of 16S rDNA
showed that the intestinal microbiota composition was perturbed after the depletion of …