Depression and Parkinson's disease: current knowledge

L Marsh - Current neurology and neuroscience reports, 2013 - Springer
L Marsh
Current neurology and neuroscience reports, 2013Springer
Depressive disturbances are common in patients with Parkinson's disease (PD) and
influence many other clinical aspects of the disease. In addition to causing inherent
emotional distress, depressive disorders negatively impact quality of life, motor and
cognitive deficits, functional disability, and other psychiatric comorbidities in patients with
PD. Knowledge of the pathophysiology of PD depression remains limited. However, clinical
studies demonstrate the efficacy of medications and psychotherapies for PD depression …
Abstract
Depressive disturbances are common in patients with Parkinson’s disease (PD) and influence many other clinical aspects of the disease. In addition to causing inherent emotional distress, depressive disorders negatively impact quality of life, motor and cognitive deficits, functional disability, and other psychiatric comorbidities in patients with PD. Knowledge of the pathophysiology of PD depression remains limited. However, clinical studies demonstrate the efficacy of medications and psychotherapies for PD depression, underscoring the importance of their timely detection and concerted management.
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