β-Amyloid precursor protein (βAPP) in human gut with special reference to the enteric nervous system
A Cabal, V Alonso-Cortina, LO Gonzalez-Vazquez… - Brain research …, 1995 - Elsevier
The distribution of the β-amyloid precursor protein (βAPP) in the human gastrointestinal
tract, from esophagus trough rectum, was studied using immunoblotting, as well as
combined immunohistochemical and image analysis (optic microdensitometry) techniques.
The study was focused on the enteric nervous system. βAPP was detected by means of a
monoclonal antibody (22C11), which recognizes all βAPP isoforms as well as βAPP-like
proteins. Immunoblotting revealed two main protein bands, one corresponding to full-length …
tract, from esophagus trough rectum, was studied using immunoblotting, as well as
combined immunohistochemical and image analysis (optic microdensitometry) techniques.
The study was focused on the enteric nervous system. βAPP was detected by means of a
monoclonal antibody (22C11), which recognizes all βAPP isoforms as well as βAPP-like
proteins. Immunoblotting revealed two main protein bands, one corresponding to full-length …