Importance Fibromyalgia is present in as much as 2% to 8% of the population, is
characterized by widespread pain, and is often accompanied by fatigue, memory problems,
and sleep disturbances. Objective To review the epidemiology, pathophysiology, diagnosis,
and treatment of fibromyalgia. Evidence Review The medical literature on fibromyalgia was
reviewed from 1955 to March 2014 via MEDLINE and the Cochrane Central Registry of
Controlled Trials, with an emphasis on meta-analyses and contemporary evidence-based …